If you know the locus name or accession number for a sequence, SeqBuilder Pro can retrieve it from the Entrez database at the National Center for Biotechnology Information (NCBI):

  1. Use File > Open Entrez Sequence or the keyboard shortcut Ctrl/Cmd+R.
  1. The Server field lists the currently selected Entrez server. You may change to a different server by selecting it from the list on the right under the globe icon; or choose A New Server and then type a new URL.

  1. In the Enter Sequence ID or Locus Name text box, type a locus name or accession number.
  1. Specify the database name using the drop-down menu.
  1. Click OK.

If the search was successful, the Save As dialog will appear. The default file name is the accession number or locus name followed by the sequence extension (.seq or .pro). After saving, the sequence will be opened as a new SeqBuilder Pro document.